BACKGROUND: The global tuberculosis epidemic results in nearly 2 million deaths and 9 million new cases of the disease a year.The vast majority of tuberculosis patients live in developing countries, where the diagnosis of tuberculosis relies on the identification of acid-fast bacilli on unprocessed sputum smears using conventional light microscopy.
Provocative poliomyelitis causing postpolio residual paralysis among select communities of two remote villages of North Karnataka in India: A community survey
Intramuscular injections can provoke muscular paralysis especially, if the child Soapstone Carvings has had exposure to polio virus.The purpose of the study was to determine the association with known risk factors for motor disabilities in two remote villages of North Karnataka (India), where an increased number of disabled people among select comm
Excess single-stranded DNA inhibits meiotic double-strand break repair.
During meiosis, self-inflicted DNA double-strand breaks (DSBs) are created by the protein Spo11 and repaired Equipment Stands by homologous recombination leading to gene conversions and crossovers.Crossover formation is vital for the segregation of homologous chromosomes during the first meiotic division and requires the RecA orthologue, Dmc1.We an
The equilibrium between antagonistic signaling pathways determines the number of synapses in Drosophila.
The number of synapses is a major determinant of behavior and many neural diseases exhibit deviations in that number.However, how signaling pathways control this number is still poorly understood.Using the Drosophila larval neuromuscular junction, we show here a PI3K-dependent pathway for synaptogenesis which is functionally connected with other pr